Parameter
| Biomarker | Ng | Full name | Neurogranin | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognostic Assessment |
| Disease | Alzheimer's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF/Plasma Exosomes (SIMOA, ELISA) | ||
| Pathobiological Mechanisms | A calmodulin-regulating protein in dendritic spines, involved in synaptic plasticity, released after synaptic injury, correlated with cognitive decline. | ||||
| Clinical Availability Status | Research validation: CSF levels are elevated in the prodromal AD stage, predicting the rate of cognitive decline. | ||||
| Notes and Dynamics | Closely correlated with tau pathology; higher CSF Ng levels are associated with faster memory function decline. | ||||