Parameter
| Biomarker | β-Syn | Full name | β-Synuclein | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis |
| Disease | Alzheimer's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/CSF (SIMOA, Immunoassay) | ||
| Pathobiological Mechanisms | A protein regulating synaptic transmission; abnormal expression promotes Aβ aggregation and tau phosphorylation. | ||||
| Clinical Availability Status | Research exploration: Plasma levels are significantly elevated in Aβ-PET positive individuals. | ||||
| Notes and Dynamics | Can distinguish AD from non-AD dementias, correlated with temporal lobe atrophy. | ||||