Parameter
| Biomarker | YKL-40 | Full name | Chitinase 3-Like Protein 1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Susceptibility Prediction |
| Disease | Alzheimer's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/CSF (ELISA, Immunoassay) | ||
| Pathobiological Mechanisms | A glycoprotein secreted by activated astrocytes, reflecting neuroinflammation; levels are elevated in AD. | ||||
| Clinical Availability Status | Research exploration: Levels in AD patients are significantly higher than those in healthy individuals, positively correlated with Aβ pathology. | ||||
| Notes and Dynamics | Involved in Aβ-induced tau pathology, can assist in assessing the degree of neuroinflammation. | ||||