Parameter
| Biomarker | SMO Mut | Full name | SMO Gene Mutation | Molecular Type | Gene Mutation |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Prediction |
| Disease | Meningioma | Disease Subtypes | / | ||
| Organ | Brain, Meninges | Test Sample / Technology Platform | Tumor Tissue (NGS, Sequencing) | ||
| Pathobiological Mechanisms | Activates the Hedgehog pathway, drives tumorigenesis, and is associated with meningothelial subtypes. | ||||
| Clinical Availability Status | Under Clinical Validation | ||||
| Notes and Dynamics | Vismodegib (SMO inhibitor) shows treatment response in mutant patients. | ||||