Parameter
| Biomarker | Procollagen type Ⅲ N-terminal peptide (PIIINP) | Full name | Procollagen type Ⅲ N-terminal peptide | Molecular Type | Protein (collagen precursor) |
|---|---|---|---|---|---|
| Molecular Formula | Human PIIINP: C₁₄₇H₂₃₁N₄₁O₄₆ | Molecular Weight | ~34.6 kDa | Core Functional Dimensions | Markers for collagen synthesis |
| Disease | Metabolic Associated Fatty Liver Disease (MASLD) | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | Hepatic stellate cells are activated, collagen synthesis is increased, and PIIINP is released into the blood, which is positively correlated with fibrosis stage | ||||
| Clinical Availability Status | It can be used clinically and is mostly used for scientific research and curative effect monitoring | ||||
| Notes and Dynamics | It can directly reflect collagen synthesis, and combined with other indicators can improve the diagnostic accuracy | ||||