Parameter
| Biomarker | pS129 α-Syn | Full name | Phosphorylated α-synuclein (S129) | Molecular Type | Protein(Modified Form) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnostic Differentiation |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF/Plasma/Erythrocytes (SIMOA, IP-MS, Western Blot) | ||
| Pathobiological Mechanisms | Hyperphosphorylation at the S129 site promotes α-syn aggregation and pathological spread. | ||||
| Clinical Availability Status | Clinical cutting-edge: Plasma testing specificity reaches 85%. | ||||
| Notes and Dynamics | Can distinguish PD from Multiple System Atrophy (MSA). | ||||