Parameter
| Biomarker | α-Syn (1-119/1-122) | Full name | α-Syn Truncated Forms (1-119/1-122) | Molecular Type | Protein(Truncated Form) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Pathological Confirmation |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF/Brain Biopsy (MS/MS, WB) | ||
| Pathobiological Mechanisms | C-terminal truncation enhances α-syn fibrillation ability, aggravating neurotoxicity. | ||||
| Clinical Availability Status | Research exploration: Levels are elevated in CSF of PD patients. | ||||
| Notes and Dynamics | Positively correlated with Lewy body density. | ||||