Parameter
| Biomarker | Seeding-Competent α-Syn | Full name | Seeding-Competent α-Syn | Molecular Type | Protein (Aggregated Form) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Early Diagnosis |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF/Skin/Colon Biopsy (RT-QuIC, PMCA) | ||
| Pathobiological Mechanisms | Amplified by RT-QuIC/PMCA, reflecting α-syn pathological activity. | ||||
| Clinical Availability Status | Clinical validation: Diagnostic sensitivity 92%, specificity 90%. | ||||
| Notes and Dynamics | Can predict the conversion of idiopathic Rapid Eye Movement Sleep Behavior Disorder (iRBD) to PD. | ||||