Parameter
| Biomarker | NfL | Full name | Neurofilament Light Chain | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease Monitoring |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF/Plasma (SIMOA, ELISA) | ||
| Pathobiological Mechanisms | Released after neuroaxonal injury, reflecting the degree of pan-neurodegeneration. | ||||
| Clinical Availability Status | Clinical monitoring tool: Used for efficacy assessment in clinical trials. | ||||
| Notes and Dynamics | Positively correlated with the progression rate of PD motor symptoms. | ||||