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488

Parameter
Biomarker DJ-1 Full name DJ-1 Protein Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Risk Stratification
Disease Parkinson's Disease Disease Subtypes /
Organ Brain Test Sample / Technology Platform CSF/Plasma (ELISA, WB)
Pathobiological Mechanisms Maintains mitochondrial function and resists oxidative stress; mutations increase PD susceptibility.
Clinical Availability Status Research exploration: CSF levels are decreased in PD patients.
Notes and Dynamics DJ-1 levels are lower in G2019S LRRK2 mutation carriers.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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