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490

Parameter
Biomarker IL-1β Full name Interleukin-1β Molecular Type Cytokine
Molecular Formula / Molecular Weight / Core Functional Dimensions Pathological Confirmation
Disease Parkinson's Disease Disease Subtypes /
Organ Brain Test Sample / Technology Platform Serum/CSF (ELISA, Luminex)
Pathobiological Mechanisms Secreted by activated microglia, activates the NF-κB pathway to promote neuroinflammation.
Clinical Availability Status Research validation: Serum levels in PD patients are 2 times higher.
Notes and Dynamics Positively correlated with the severity of PD motor symptoms.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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