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496

Parameter
Biomarker UA Full name Uric Acid Molecular Type Metabolite
Molecular Formula C5H4N4O3 Molecular Weight 168.11 g/mol Core Functional Dimensions Risk Stratification
Disease Parkinson's Disease Disease Subtypes /
Organ Brain Test Sample / Technology Platform Plasma (Uric Acid Kit, HPLC)
Pathobiological Mechanisms Resists oxidative stress; decreased levels lead to increased vulnerability of dopaminergic neurons.
Clinical Availability Status Research validation: Plasma levels in PD patients are 25% lower than those in healthy individuals.
Notes and Dynamics Can be used as a non-invasive indicator for PD risk screening.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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