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497

Parameter
Biomarker FFA10:0/FFA12:0 Full name Free Fatty Acids (FFA10:0/FFA12:0) Molecular Type Metabolite
Molecular Formula C10H20O2/C12H24O2 Molecular Weight 172.26/200.32 g/mol Core Functional Dimensions Early Diagnosis
Disease Parkinson's Disease Disease Subtypes /
Organ Brain Test Sample / Technology Platform Plasma (LC-MS, GC-MS)
Pathobiological Mechanisms Lipid metabolism imbalance affects α-syn aggregation and synaptic function.
Clinical Availability Status Research exploration: Plasma levels are significantly decreased in PD patients.
Notes and Dynamics Negatively correlated with PD motor score (UPDRS III).

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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