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499

Parameter
Biomarker PAG Full name Phenylacetylglutamine Molecular Type Metabolite
Molecular Formula C11H14N2O3 Molecular Weight 222.24 g/mol Core Functional Dimensions Pathological Confirmation
Disease Parkinson's Disease Disease Subtypes /
Organ Brain Test Sample / Technology Platform Plasma (LC-MS, GC-MS)
Pathobiological Mechanisms Abnormal amino acid metabolism, involved in PD neurotoxic pathways.
Clinical Availability Status Research exploration: Plasma levels are elevated in PD patients.
Notes and Dynamics Positively correlated with the degree of PD cognitive impairment.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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