Parameter
| Biomarker | KYN | Full name | Kynurenine | Molecular Type | Metabolite |
|---|---|---|---|---|---|
| Molecular Formula | C10H12N2O3 | Molecular Weight | 208.21 g/mol | Core Functional Dimensions | Pathological Confirmation |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/CSF (LC-MS, GC-MS) | ||
| Pathobiological Mechanisms | Kynurenine pathway imbalance produces the neurotoxic metabolite quinolinic acid. | ||||
| Clinical Availability Status | Research exploration: Levels in PD patients are positively correlated with neuroinflammation. | ||||
| Notes and Dynamics | Pathway inhibitors can reduce neuronal injury in PD models. | ||||