Parameter
| Biomarker | APOE ε4 | Full name | Apolipoprotein E ε4 | Molecular Type | Nucleic Acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Risk Stratification |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Whole Blood (Genotyping, PCR) | ||
| Pathobiological Mechanisms | Affects α-syn clearance and lipid metabolism, increasing PD onset risk. | ||||
| Clinical Availability Status | Clinically available: Routine genetic testing item. | ||||
| Notes and Dynamics | ε4 homozygotes have a 3-fold increased risk of PD. | ||||