Parameter
| Biomarker | SNCA Mut (A53T/A30P) | Full name | SNCA Mutants (A53T/A30P) | Molecular Type | Nucleic Acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Risk Stratification |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Whole Blood (Gene Sequencing, PCR) | ||
| Pathobiological Mechanisms | Promotes α-syn aggregation, pathogenic mutations for familial PD. | ||||
| Clinical Availability Status | Clinically available: Used for genetic counseling of familial PD. | ||||
| Notes and Dynamics | A53T mutation carriers have higher CSF pS129 α-syn levels. | ||||