Parameter
| Biomarker | miR-124 | Full name | MicroRNA-124 | Molecular Type | Non-coding RNA (microRNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Early Diagnosis |
| Disease | Parkinson's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/CSF (qPCR, RNA-seq) | ||
| Pathobiological Mechanisms | Inhibits BACE1 expression, regulates α-syn metabolism; levels are decreased in PD. | ||||
| Clinical Availability Status | Research exploration: Plasma levels in PD patients are 40% lower than those in healthy individuals. | ||||
| Notes and Dynamics | Exogenous miR-124 can reduce α-syn aggregation in PD models. | ||||