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508

Parameter
Biomarker RNFL Full name Retinal Nerve Fiber Layer Thickness Molecular Type Imaging Biomarker (Ophthalmic)
Molecular Formula / Molecular Weight / Core Functional Dimensions Disease Monitoring
Disease Parkinson's Disease Disease Subtypes /
Organ Brain Test Sample / Technology Platform Fundus (Optical Coherence Tomography, OCT)
Pathobiological Mechanisms Reflects intracerebral neurodegenerative injury; thickness is decreased in PD patients.
Clinical Availability Status Research validation: RNFL thickness in PD patients is 10% less than that in healthy individuals.
Notes and Dynamics Can be used as a non-invasive monitoring indicator for PD.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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