Parameter
| Biomarker | GABA-B R Ab | Full name | GABA-B Receptor Antibody | Molecular Type | Autoantibody |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Etiology |
| Disease | Epilepsy | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Serum/Cerebrospinal Fluid (ELISA, Cell-based Assay) | ||
| Pathobiological Mechanisms | Binds to GABA-B receptors, inhibits inhibitory neurotransmission, leading to hyperexcitability of the neuronal network. | ||||
| Clinical Availability Status | Under clinical validation | ||||
| Notes and Dynamics | Often accompanied by limbic encephalitis, associated with refractory epilepsy; immunotherapy can improve prognosis. | ||||