Parameter
| Biomarker | Alanine aminotransferase (ALT) | Full name | Alanine aminotransferase | Molecular Type | Enzymes |
|---|---|---|---|---|---|
| Molecular Formula | Human ALT: C₁₁₀₇H₁₇₅₃N₂₉₃O₃₃₁S₆ | Molecular Weight | ~120 kDa | Core Functional Dimensions | Liver injury detection, disease diagnosis and prognosis evaluation |
| Disease | Viral Hepatitis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum | ||
| Pathobiological Mechanisms | It is mainly expressed in the liver and released into the blood when hepatocytes are injured. It is a sensitive indicator of liver injury. It can reflect the degree of liver inflammation, and is related to viral replication and metabolic disorders. The fluctuation of its level can indicate the progression of disease and the response to treatment | ||||
| Clinical Availability Status | Markers are routinely used in clinical practice | ||||
| Notes and Dynamics | Although the classic and cost-effective core markers are affected by factors such as age and gender, they are still the key tools for early detection and efficacy monitoring of chronic liver disease, and the diagnostic accuracy should be optimized in combination with other indicators | ||||