Parameter
| Biomarker | Hepatitis B core-related antigen (HBcrAg) | Full name | Hepatitis B core-related antigen | Molecular Type | Proteins |
|---|---|---|---|---|---|
| Molecular Formula | Human HBcrAg (HBcAg+HBeAg): C₄₁₂H₆₄₇N₁₁₉O₁₃₀S₄ | Molecular Weight | ~92 kDa | Core Functional Dimensions | Virus replication monitoring, prognosis assessment, recurrence prediction |
| Disease | Viral Hepatitis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum | ||
| Pathobiological Mechanisms | It contains HBcAg, HBeAg and other proteins, which are highly correlated with cccDNA levels and can reflect the viral replication status. It can predict the risk of liver fibrosis, cirrhosis and liver cancer, and guide the timing of drug withdrawal | ||||
| Clinical Availability Status | Clinical research phase (used in clinical practice in some areas) | ||||
| Notes and Dynamics | It is suitable for rapid detection in resource-limited areas. It is an important candidate marker for precise management of chronic hepatitis B, and needs to be further validated to establish a unified standard | ||||