Parameter
| Biomarker | Fibrin-like protein 1 (FGL1) | Full name | Fibrin-like protein 1 | Molecular Type | Proteins |
|---|---|---|---|---|---|
| Molecular Formula | Human FGL1: C₆₉₉H₁₁₀₇N₁₈₉O₂₁₀S₆ | Molecular Weight | ~156 kDa | Core Functional Dimensions | Liver injury repair, metabolic regulation, tumor immunity |
| Disease | Viral Hepatitis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum, tumor tissue | ||
| Pathobiological Mechanisms | Promote hepatocyte proliferation and liver regeneration, participate in lipid metabolism; As LAG-3 ligand, it inhibits T cell activity and promotes tumor immune escape, which is related to the progression of liver cancer | ||||
| Clinical Availability Status | Clinical research phase | ||||
| Notes and Dynamics | It has a protective effect in the repair of liver injury, but has a carcinogenic effect in liver cancer, and its function is dual. As an immunotherapy target and disease marker, it has potential clinical transformation value, and the mechanism of action needs to be further clarified | ||||