Parameter
| Biomarker | Gamma-glutamyltransferase (GGT) | Full name | Gamma-glutamyltransferase | Molecular Type | Enzymes |
|---|---|---|---|---|---|
| Molecular Formula | Human GGT: C₁₁₇₆H₁₈₄₈N₃₀₈O₃₄₈S₁₂ | Molecular Weight | ~130 kDa | Core Functional Dimensions | Evaluation of cholestasis, diagnosis of alcoholic liver disease, and monitoring of metabolic abnormalities |
| Disease | Viral Hepatitis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum | ||
| Pathobiological Mechanisms | It is mainly present in hepatobiliary cells and increases in cholestasis and alcohol intake. It is positively correlated with the severity of alcohol-related liver disease (ALD). And can be used as an auxiliary marker of metabolic syndrome such as MASLD | ||||
| Clinical Availability Status | Routine clinical use | ||||
| Notes and Dynamics | It has high sensitivity but low specificity, and should be judged comprehensively in combination with clinical background (such as drinking history and other enzyme indicators). It is an important auxiliary diagnostic indicator for alcoholic liver disease and cholestatic diseases | ||||