Parameter
| Biomarker | Platelet Count (PLT) | Full name | Platelet Count | Molecular Type | Cell types |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis of liver cirrhosis and evaluation of portal hypertension | ||
| Disease | Viral Hepatitis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Whole blood | ||
| Pathobiological Mechanisms | Thrombocytopenia due to hypersplenism in liver cirrhosis; PLT < 100×10⁹/L indicates the risk of portal hypertension; Combination of AST/ALT ratio (e.g., APRI index) can improve the accuracy of liver fibrosis assessment | ||||
| Clinical Availability Status | Routine clinical use | ||||
| Notes and Dynamics | Simple and easily available auxiliary markers of liver cirrhosis, although with low specificity (other diseases can also lead to PLT reduction), combined with other indicators (such as APRI and FIB-4) can significantly improve the clinical value and is an important screening tool in the primary care setting | ||||