Parameter
| Biomarker | HBsAg (hepatitis B surface antigen) | Full name | Hepatitis B surface antigen | Molecular Type | Protein (viral antigen) |
|---|---|---|---|---|---|
| Molecular Formula | Human HBsAg: C₂₂₆H₃₄₈N₅₄O₆₂S₂ | Molecular Weight | ~24 kDa | Core Functional Dimensions | Diagnosis, infection status determination |
| Disease | Viral Hepatitis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (ELISA, chemiluminescence) | ||
| Pathobiological Mechanisms | The surface protein of hepatitis B virus (HBV) expressed in liver cells after infection is a marker of viral infection. Persistent positivity indicates chronic infection. | ||||
| Clinical Availability Status | Clinical routine use: core screening and diagnostic markers, widely used. | ||||
| Notes and Dynamics | The first choice for screening hepatitis B virus infection is simple to operate and the cost is controllable, but its negative result cannot completely exclude infection (such as occult hepatitis B), so it needs to be combined with other indicators for comprehensive judgment. | ||||