Parameter
| Biomarker | Liver enzymes (ALT/AST) | Full name | Alanine Aminotransferase / Aspartate Aminotransferase | Molecular Type | Proteins (enzymes) |
|---|---|---|---|---|---|
| Molecular Formula | Human ALT: C₁₁₀₇H₁₇₅₃N₂₉₃O₃₃₁S₆; Human AST: C₁₁₁₃H₁₇₆₁N₂₉₅O₃₃₅S₆ | Molecular Weight | ALT: ~120 kDa; AST: ~121 kDa | Core Functional Dimensions | Liver injury monitoring and disease assessment |
| Disease | Viral Hepatitis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (biochemical analysis, colorimetry) | ||
| Pathobiological Mechanisms | When liver cells are damaged, intracellular ALT/AST are released into the blood, and the degree of increase in enzyme activity is positively correlated with the extent and severity of liver cell injury. | ||||
| Clinical Availability Status | Clinical routine use: general liver injury monitoring index, non-specific. | ||||
| Notes and Dynamics | Sensitive indicators reflecting liver cell injury can quickly indicate liver inflammation or injury, but lack etiological specificity. It is necessary to combine with virological markers to determine whether it is caused by viral hepatitis. | ||||