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927

Parameter
Biomarker CYFRA 21-1 Full name Cytokeratin 19 fragment Molecular Type Protein (cytokeratin 19 fragment)
Molecular Formula Protein fragment Molecular Weight ~40 kDa Core Functional Dimensions Diagnosis and Prognosis
Disease Cholangiocarcinoma (CCA) Disease Subtypes /
Organ Bile duct/Liver Test Sample / Technology Platform Serum (Immunoassay)
Pathobiological Mechanisms Cholangiocarcinoma cells are released after apoptosis, reflecting tumor burden, and the increase is not obvious in benign biliary diseases
Clinical Availability Status Research validation; It is more specific than CA19-9
Notes and Dynamics

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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