Parameter
| Biomarker | MMP-7 | Full name | Matrix metalloproteinase-7 | Molecular Type | Protein (matrix metalloproteinase 7) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | ~28 kDa (proenzyme) | Core Functional Dimensions | Diagnosis and Prognosis | |
| Disease | Cholangiocarcinoma (CCA) | Disease Subtypes | / | ||
| Organ | Bile duct/Liver | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | It degrades extracellular matrix and promotes tumor invasion, metastasis, and angiogenesis | ||||
| Clinical Availability Status | Study validation; It can distinguish malignant from benign biliary obstruction | ||||
| Notes and Dynamics | In patients with obstructive jaundice, elevated levels suggest the possibility of iCCA, and preoperative levels are associated with the risk of postoperative recurrence | ||||