Parameter
| Biomarker | Osteopontin | Full name | Osteopontin | Molecular Type | Protein (osteopontin) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | ~44 kDa | Core Functional Dimensions | Diagnosis and Prognosis | |
| Disease | Cholangiocarcinoma (CCA) | Disease Subtypes | / | ||
| Organ | Bile duct/Liver | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | It is involved in cell adhesion, migration and survival, and promotes tumor progression and metastasis; And regulate the tumor microenvironment | ||||
| Clinical Availability Status | Study validation; And is associated with postoperative survival | ||||
| Notes and Dynamics | Elevated preoperative serum levels indicate poor prognosis and can be used as an indicator of recurrence risk assessment. The serum level in iCCA patients was significantly higher than that in benign biliary diseases | ||||