Parameter
| Biomarker | FGFR2 (fusion/rearrangement) | Full name | Fibroblast growth factor receptor 2 fusions | Molecular Type | Nucleic acid (DNA fusion) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, targeted therapy selection, prognosis | ||
| Disease | Cholangiocarcinoma (CCA) | Disease Subtypes | / | ||
| Organ | Bile duct/Liver | Test Sample / Technology Platform | Tissue/plasma/bile (NGS, FISH) | ||
| Pathobiological Mechanisms | Fusion activation FGFR signaling pathways, and promote the tumor proliferation and angiogenesis | ||||
| Clinical Availability Status | Clinically available (targeted therapy options); ICCA detection rate of 10-15% | ||||
| Notes and Dynamics | |||||