Parameter
| Biomarker | CTCs (circulating tumor cells) | Full name | Circulating tumor cells | Molecular Type | cells |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognosis, metastasis, MRD monitoring | ||
| Disease | Cholangiocarcinoma (CCA) | Disease Subtypes | / | ||
| Organ | Bile duct/Liver | Test Sample / Technology Platform | Whole blood (CellSearch, microfluidic technology) | ||
| Pathobiological Mechanisms | Tumor cells fall off into the bloodstream, transfer of precursor, reflect the tumor invasion ability | ||||
| Clinical Availability Status | The validation; The detection sensitivity needs to be improved | ||||
| Notes and Dynamics | CTCs ≥2 indicates poor prognosis. Joint ctDNA detection can increase the efficiency of the MRD monitoring (AUC) 0.92, is better than that of CA19-9 | ||||