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953

Parameter
Biomarker AFP-L3 Full name Lectin-reactive alpha-fetoprotein fraction (Lens culinaris agglutinin-reactive AFP) Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis and Prognosis
Disease Hepatocellular Carcinoma (HCC) - Disease Subtypes /
Organ Liver Test Sample / Technology Platform Serum (affinity electrophoresis, ELISA)
Pathobiological Mechanisms AFP different plasmids, associated with malignant degree of liver cancer cells
Clinical Availability Status Clinical validation: used for additional diagnosis of HCC with negative AFP or low levels
Notes and Dynamics The core components of GALAD model can improve the diagnostic specificity of early HCC

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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