Parameter
| Biomarker | Glypican - 3 (GPC3) | Full name | Glypican-3 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, Prognosis | ||
| Disease | Hepatocellular Carcinoma (HCC) - | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Tumor tissue/serum (IHC, ELISA) | ||
| Pathobiological Mechanisms | Liver cancer cell surface glycoprotein, activate the Wnt signaling pathway to promote proliferation | ||||
| Clinical Availability Status | Research validation: IHC is used for pathological diagnosis, and serum detection is in the clinical trial stage | ||||
| Notes and Dynamics | EV-derived GPC3 mRNA is a potential marker for early detection | ||||