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Parameter
Biomarker Osteopontin (SPP1) Full name Secreted phosphoprotein 1 (Osteopontin) Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, Prognosis
Disease Hepatocellular Carcinoma (HCC) - Disease Subtypes /
Organ Liver Test Sample / Technology Platform Serum (ELISA)
Pathobiological Mechanisms Tumor microenvironment secreted protein, and promote the tumor invasion and angiogenesis
Clinical Availability Status Study validation: the expression was increased in early HCC and correlated with recurrence
Notes and Dynamics It can be used as an auxiliary indicator for prognostic risk stratification

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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