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961

Parameter
Biomarker Midkine (MDK) Full name Midkine Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, Prognosis
Disease Hepatocellular Carcinoma (HCC) Disease Subtypes /
Organ Hepatocellular Carcinoma (HCC) Test Sample / Technology Platform Serum (ELISA)
Pathobiological Mechanisms Heparin combined with growth factors, promote cell proliferation and metastasis of liver cancer
Clinical Availability Status The validation: high sensitivity for AFP negative HCC diagnosis
Notes and Dynamics It shows potential in differentiating early-stage HCC from cirrhosis

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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