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965

Parameter
Biomarker Cell-free DNA (cfDNA) Full name Cell-free DNA Molecular Type Nucleic acid (DNA)
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, prognosis, and monitoring
Disease Hepatocellular Carcinoma (HCC) - Disease Subtypes /
Organ Liver Test Sample / Technology Platform Plasma (NGS, NEEM-seq)
Pathobiological Mechanisms There are differences in the characteristics of circulating cell-free DNA between HCC patients and healthy people, reflecting tumor burden
Clinical Availability Status Research validation: age, AFP building model, specificity of 100%
Notes and Dynamics The combined detection of 5hmC and 5mC can improve the accuracy of recurrence prediction

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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