Parameter
| Biomarker | Cell-free DNA (cfDNA) | Full name | Cell-free DNA | Molecular Type | Nucleic acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, and monitoring | ||
| Disease | Hepatocellular Carcinoma (HCC) - | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Plasma (NGS, NEEM-seq) | ||
| Pathobiological Mechanisms | There are differences in the characteristics of circulating cell-free DNA between HCC patients and healthy people, reflecting tumor burden | ||||
| Clinical Availability Status | Research validation: age, AFP building model, specificity of 100% | ||||
| Notes and Dynamics | The combined detection of 5hmC and 5mC can improve the accuracy of recurrence prediction | ||||