Parameter
| Biomarker | MiR - 21, miR - 122, miR - 192, miR - 26 a, a miR - 29 (including organization/circular) | Full name | MicroRNAs (e.g., miR-21, miR-122, miR-192, miR-26a, miR-29) | Molecular Type | Nucleic acid (RNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, predict treatment response | ||
| Disease | Hepatocellular Carcinoma (HCC) - | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum/plasma/tumor tissue (qRT-PCR, NGS) | ||
| Pathobiological Mechanisms | It regulates the expression of oncogenes/tumor suppressor genes and participates in tumor proliferation, invasion and drug resistance | ||||
| Clinical Availability Status | Research validation: many micrornas panel in the diagnosis of early HCC AUC 0.824 to 0.977 | ||||
| Notes and Dynamics | miR-21 was associated with sorafenib resistance, and miR-1246 could predict early recurrence after surgery | ||||