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Parameter
Biomarker miR-9, miR-17-5p, miR-21, miR-1246, etc. (Circular) Full name Circular and other microRNAs Molecular Type Nucleic acid (RNA)
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis, Surveillance
Disease Hepatocellular Carcinoma (HCC) Disease Subtypes /
Organ Liver Test Sample / Technology Platform Serum/plasma/plasma exosomes (qRT-PCR, digital PCR)
Pathobiological Mechanisms Circulating mirnas have high stability, and their expression changes reflect tumor progression and treatment response
Clinical Availability Status Validation: multiple studies confirm related to OS, DFS
Notes and Dynamics Secrete body outside the miRNA detection sensitivity is better than that of free micrornas, is a hot spot in the liquid biopsy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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