Parameter
| Biomarker | MALAT1, LINC00152, Linc00974 etc | Full name | Long non-coding RNAs (e.g., MALAT1, LINC00152, Linc00974) | Molecular Type | Nucleic acids (RNA, long non-coding RNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and Prognosis | ||
| Disease | Hepatocellular Carcinoma (HCC) | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum/tumor tissue (qRT - PCR, RNA - seq) | ||
| Pathobiological Mechanisms | Control the miRNA expression or chromatin reconstruction, promote EMT and tumor metastasis | ||||
| Clinical Availability Status | Cutting-edge research: serum LINC00152 can distinguish between HCC and liver cirrhosis | ||||
| Notes and Dynamics | Combined with AFP, LINC00152 can improve the diagnostic specificity and is expected to be included in the composite marker panel | ||||