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Parameter
Biomarker Atezolizumab-Bevacizumab Response Signature (ABRS) Full name Atezolizumab-Bevacizumab Response Signature Molecular Type Nucleic acid (RNA signature)
Molecular Formula Molecular Weight Core Functional Dimensions Predicting treatment response
Disease Hepatocellular Carcinoma (HCC) Disease Subtypes /
Organ Liver Test Sample / Technology Platform Tumor tissue (RNA-seq)
Pathobiological Mechanisms Based on multi-gene expression characteristics, it reflects the status of tumor immunity and angiogenesis
Clinical Availability Status Research validation: high expression patients received combination therapy PFS is prolonged
Notes and Dynamics This study provides a molecular basis for the selection of patients for combination therapy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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