Parameter
| Biomarker | PRO-C3 | Full name | N-terminal propeptide of type III collagen | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, Prognosis | ||
| Disease | Liver Cirrhosis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | Reflect the type III collagen synthesis, associated with hepatic stellate cell activation, is the key to the progress of liver fibrosis markers. | ||||
| Clinical Availability Status | Clinical validation: in alcoholic liver disease, MASLD related cirrhosis has proven its level associated with the degree of fibrosis, and can be used to assess disease progression and response to treatment. | ||||
| Notes and Dynamics | Can distinguish between liver fibrosis and other liver diseases, combined other markers can improve the diagnostic accuracy, and is the important index prediction of the progress of cirrhosis. | ||||