Parameter
| Biomarker | C4M | Full name | MMP-generated neoepitope of type IV collagen | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, Monitoring | ||
| Disease | Liver Cirrhosis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | It reflects that type IV collagen is degraded by matrix metalloproteinases (MMP) and is associated with the progression of liver inflammation and fibrosis. | ||||
| Clinical Availability Status | Studies have verified that the level of serum is increased in chronic hepatitis-related cirrhosis, which can reflect the state of liver tissue damage and repair. | ||||
| Notes and Dynamics | It is correlated with systemic inflammatory markers and can be used to evaluate the dynamic damage process of liver tissue in patients with liver cirrhosis. | ||||