Parameter
| Biomarker | VICM | Full name | MMP-generated citrullinated vimentin fragment | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Monitoring, prognosis | ||
| Disease | Liver Cirrhosis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (specific antigen detection) | ||
| Pathobiological Mechanisms | Citrullinated vimentin is the product of MMP degradation, which reflects the activation of macrophages. | ||||
| Clinical Availability Status | Studies verified that it was elevated in viral hepatitis and MASLD-related cirrhosis, and correlated with liver fibrosis activity. | ||||
| Notes and Dynamics | It can be used as a monitoring index of inflammation activity in patients with liver cirrhosis and to predict treatment response. | ||||