Parameter
| Biomarker | Procollagen type III N-terminal peptide (PIIINP) | Full name | N-terminal propeptide of type III procollagen | Molecular Type | Proteins |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and surveillance | ||
| Disease | Liver Cirrhosis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (radioimmunoassay, ELISA) | ||
| Pathobiological Mechanisms | It reflects the synthesis of type III collagen and its release is increased in liver fibrosis, which is associated with the progression of cirrhosis. | ||||
| Clinical Availability Status | Clinical application: to evaluate the activity of liver cirrhosis, and response to treatment is one of the commonly used serum liver fibrosis markers. | ||||
| Notes and Dynamics | In the early liver fibrosis can be increased and can be used for liver cirrhosis early screening and monitoring. | ||||