Parameter
| Biomarker | Matrix metalloproteinase inhibitor-1 (TIMP-1) | Full name | Tissue inhibitor of metalloproteinases 1 | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, Prognosis | ||
| Disease | Liver Cirrhosis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | Inhibition of matrix metalloproteinase activity leads to decreased collagen degradation and promotes ECM deposition. | ||||
| Clinical Availability Status | Clinical exploration: Levels are elevated in patients with cirrhosis and positively correlated with the degree of fibrosis. | ||||
| Notes and Dynamics | It can be used as an auxiliary indicator for the prognosis evaluation of liver cirrhosis, and the continuous increase of its level indicates an increased risk of disease progression. | ||||