Parameter
| Biomarker | Circulating cell-free DNA (cfDNA) | Full name | Cell-free DNA | Molecular Type | Nucleic acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and monitoring | ||
| Disease | Liver Cirrhosis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | Plasma (next generation sequencing, digital PCR) | ||
| Pathobiological Mechanisms | In liver tissue damage when released into the blood, reflecting the liver cell apoptosis and liver tissue damage degree. | ||||
| Clinical Availability Status | Frontier research: Elevated levels in patients with cirrhosis and associated with disease severity and risk of complications. | ||||
| Notes and Dynamics | It has the advantage of non-invasive, and can be used for real-time monitoring of liver tissue damage and repair in patients with liver cirrhosis. | ||||