Parameter
| Biomarker | BAP1 Mut | Full name | BAP1 Gene Mutation | Molecular Type | Gene Mutation |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Prognosis |
| Disease | Meningioma | Disease Subtypes | / | ||
| Organ | Brain, Meninges | Test Sample / Technology Platform | Tumor Tissue (NGS, Immunohistochemistry) | ||
| Pathobiological Mechanisms | Regulates DNA damage repair; mutations lead to a malignant phenotype and are associated with rhabdoid subtypes. | ||||
| Clinical Availability Status | Research Validation Stage | ||||
| Notes and Dynamics | A specific biomarker for WHO Grade III meningiomas, with a significantly increased recurrence risk. | ||||