Parameter
| Biomarker | IL-6 | Full name | Interleukin 6 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Prognosis |
| Disease | Depression | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/Serum (ELISA, Electrochemiluminescence Immunoassay) | ||
| Pathobiological Mechanisms | Pro-inflammatory factor activates brain microglia, inhibits hippocampal neurogenesis, and promotes tryptophan metabolism toward the neurotoxic kynurenine pathway. | ||||
| Clinical Availability Status | Under Clinical Validation | ||||
| Notes and Dynamics | Synergizes with excessive HPA axis activation; combined with BDNF detection can improve the diagnostic accuracy to 82%. | ||||