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632

Parameter
Biomarker IL-10 Full name Interleukin 10 Molecular Type Protein
Molecular Formula C153H238N40O47 Molecular Weight 3430.82 g/mol Core Functional Dimensions Prognosis, Disease Monitoring
Disease Depression Disease Subtypes /
Organ Brain Test Sample / Technology Platform Plasma (ELISA)
Pathobiological Mechanisms Insufficient anti-inflammatory factors lead to neuroinflammatory imbalance, unable to antagonize the neurotoxic effects of IL-6/TNF-α.
Clinical Availability Status RResearch Stage
Notes and Dynamics IL-10 levels increase more than 2-fold in patients with effective antidepressant treatment, serving as a treatment response biomarker.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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